We may not all be able to live to 85, 90 or 100, but new clues about the unique biology of those who do can provide actionable intelligence for living healthy for as long as possible.
Awesome summary, thank you. Super positive when new research confirms we have a great chance to age well when we do the things we definitevly know are good for us!
Tash, I’m glad this was helpful to you. You said it very well: doing the things we know for sure are good for us—moving our bodies with purpose; eating whole foods (I know that that’s your specialty); sleep and remaining social—gives more healthy years the best chance of becoming reality. Keep going.
I’m curious about this as well. I came across an article recently about the benefit of ubiquinol in improving mitochondrial function through oxidative phosphorylation…a mouthful but it was intriguing.
Patty, I would look long and hard before buying that particular supplement. I actually wrote about it in this Note, which is a follow up of my article on Dr. Mark Hyman. The research he cites for this supplement was written by people who work for the company that manufactures it. But he doesn't mention that to his customers. https://substack.com/@pvonz/note/c-221990943?r=88kaf&utm_medium=ios&utm_source=notes-share-action
The paper does not track what subjects ate, how much they walked, their sleep patterns, social engagement or any other behavioral or lifestyle variables, unfortunately. It's unit of analysis is blood proteins, not behavior. (The researchers drew blood from 39 Swiss centenarians 100–105 yrs old, a few dozen hospitalized octogenarians (aged 80–90) and 40 healthy younger adults aged 30–60, then measured 724 proteins across inflammatory and cardiovascular panels. The paper studied material collected as part of something called The SWISS100 Project, if further researching this subject is of interest.
Awesome summary, thank you. Super positive when new research confirms we have a great chance to age well when we do the things we definitevly know are good for us!
Tash, I’m glad this was helpful to you. You said it very well: doing the things we know for sure are good for us—moving our bodies with purpose; eating whole foods (I know that that’s your specialty); sleep and remaining social—gives more healthy years the best chance of becoming reality. Keep going.
Paul- what can you us about mitichondrial supplements?
Patty, good question. Let me start digging into it.
I’m curious about this as well. I came across an article recently about the benefit of ubiquinol in improving mitochondrial function through oxidative phosphorylation…a mouthful but it was intriguing.
Great! Thank you! I have been seeing a lot of hype about Mito pure urolithin. Most of the reviews seem to be by a site called “Timeline.”
Patty, I would look long and hard before buying that particular supplement. I actually wrote about it in this Note, which is a follow up of my article on Dr. Mark Hyman. The research he cites for this supplement was written by people who work for the company that manufactures it. But he doesn't mention that to his customers. https://substack.com/@pvonz/note/c-221990943?r=88kaf&utm_medium=ios&utm_source=notes-share-action
Do they have a breakdown on what they are and how much are they walking?
Abdurahman, do you mean what the 37 proteins are in the Swiss cententarian study, and how much those people walk?
What their diet was and how much they walked daily. Or in general what is their movement routine
The paper does not track what subjects ate, how much they walked, their sleep patterns, social engagement or any other behavioral or lifestyle variables, unfortunately. It's unit of analysis is blood proteins, not behavior. (The researchers drew blood from 39 Swiss centenarians 100–105 yrs old, a few dozen hospitalized octogenarians (aged 80–90) and 40 healthy younger adults aged 30–60, then measured 724 proteins across inflammatory and cardiovascular panels. The paper studied material collected as part of something called The SWISS100 Project, if further researching this subject is of interest.
Super-agers quietly prove something important:
Aging is not just time passing.
It’s how systems respond to time.